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Thursday, December 15, 2005

Evidence for Success of Embryonic Stem Cells Was Faked, Scientist Admits

I'll never understand the attraction of embryonic stem cells (other than as a way of making some good come from abortions and human cloning), for they have no practical use and show little to no real promise of ever having any, whereas adult stem cells (ASCs, including umbilical cord cells) are successfully doing so much good and have been doing so for several years. (Ever heard of the wonders of bone marrow transplants? That's a common use of ASCs.) The benefits of ESCs are perpetually on the horizon and never actually achieved, whereas ASCs are doing much good and show clear promise of doing much, much more if only sufficient resources were directed to the effort.

Accordingly, it should come as no surprise when the Times of London reports that one of the most prominent alleged successes of ESCs was in fact fabricated, and the scientist has admitted it:

The scientist who led the world in pioneering human cloning faked much of the data for his landmark research into embryonic stem (ES) cells, one of his close collaborators said today.

Woo Suk Hwang has admitted to fabricating key parts of a study that purported to show the creation of the first human master cells tailor-made to match individual patients, according to Sung il Roh, a senior colleague at his laboratory in Seoul, South Korea.

Dr Roh said that nine of the 11 colonies of stem cells featured in the study, which was published to worldwide acclaim in May in the prestigious journal Science, had not been authentic. The validity of the other two is still uncertain.

He said Dr Hwang had admitted to flaws in the study when Dr Roh visited him today in hospital, where the scientist is being treated for exhaustion. Both researchers had then agreed to ask Science formally to retract their paper. "Professor Hwang admitted to fabrication," Dr Roh told the MBC, a Korean television station. "Hwang said there were no cloned embryonic stem cells at all and he did not know that."

What is at fault here is the excessive enthusiasm for ESCs, which is far beyond the bounds of what they have accomplished or can realistically be expected to achieve, especially in comparison with ASCs. When the press start praising the authentic, documented achievements of ASCs with one-tenth the enthusiasm with which they greet the meager work that has been done with ESCs, the temptation to cheat in favor of finding false hopeful results for the latter will decrease accordingly.

1 comment:

James F. Elliott said...

It turns out that this article Mr. Karnick is referring to is a bit jumping the gun. Dr. Roh, one of the research partners, is saying the evidence was fabricated. However, Dr. Hwang, the principle author and researcher, says he is withdrawing the article in question due to errors and flaws in the data reporting as written in the report, not the methodology. Indeed, the researcher who Dr. Roh claims Dr. Hwang pressured to falsify data, Kim Sun-jong of the University of Pittsburgh, denies Dr. Roh's claim and vouches for the eight stem-cell lines in question.

What's occurring here is a he said-he said between Roh and Hwang.